Healthy vision offers patients more than good eyesight; for many, their quality of life is greatly diminished if their vision is less than adequate. For example, needing help reading a menu or being nervous to drive at night can limit patients’ independence, but nutritional support can help maintain long- term eye health. Perhaps some of the most talked-about antioxidants necessary for healthy vision are zeaxanthin and lutein, but why all the excitement around these two nutrients?

What’s all the hype about Zeaxanthin and Lutein?

Zeaxanthin (pronounced zee-aZAN-thin)

Zeaxanthin is a member of a group of compounds known as carotenoids.1  In the Zeaxanthin and Visual Function (ZVF) Study, researchers refer to this carotenoid as a “superior antioxidant” because of its chemical structure.2  In the same study, authors remark that “the macula selectively places [zeaxanthin] in its foveal center where the greatest protection is needed, which is last to degenerate.” This means that zeaxanthin is responsible for protecting the crisp, clear central vision needed for reading, seeing faces, and other daily tasks. While this antioxidant can be found in orange peppers, corn, and spinach, many Americans do not consume enough of these foods in their diet. 

Lutein (pronounced LOO- teen)

Like zeaxanthin, lutein is also classified as a carotenoid. Accumulated by the retina in the peripheral aspect of the macula, this antioxidant protects peripheral vision and low-contrast visual acuity.2 Lutein can be found in dark, leafy greens like kale, spinach, broccoli, and collard greens. While most patients know that these foods are beneficial, Americans sadly have moved toward a diet lacking in leafy greens. 

Macular Pigment 

Zeaxanthin and lutein work together to protect the sensitive tissues in the retina and form what is called the xanthophyll macular pigment. Found in the center of the macula, this protective pigment works like internal sunglasses, filtering harmful wavelengths of light before they reach the photoreceptors. Healthy, or dense, macular pigment may improve visual functions such as visual acuity, contrast sensitivity, light sensitivity, and glare recovery. 

From Review of Optometry Online May 10, 2018.

Sources: 

1. Heiting, Gary. “Lutein and Zeaxanthin – Eye and Vision Benefits.” All About Vision, AAV Media, LLC., Dec. 2017, www.allaboutvision.com/nutrit ion/lutein.htm. 

2. Richer SP, Stiles W, Graham-Hoffman K, et al. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Optometry. 2011 Nov;82(11):667-680.e6. doi: 10.1016/j.optm.2011.08.008. 

3. Herman JP, Kleiner-Goudey SJ, Davis RL (2017) Case Report of Dietary Supplements Improving Macular Pigment and Visual Function. Adv Oph thalmol Vis Syst 6(1): 00166. DOI: 10.15406/aovs.2017.06.00166. 

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